(R) -6',7'-Dihydroxybergamottin
(R) -6',7'-Dihydroxybergamottin ((R) -6′,7′-DHB) is a competitive inhibitor of human and rat CYP1A1 activity with Kis of 55 μM and 1.72 μM, respectively. (R) -6',7'-Dihydroxybergamottin has the potential for cancer research[1].
Product Specifications
CAS Number
[264234-05-1]
Product Name Alternative
(R) -6′,7′-DHB
UNSPSC
12352005
Target
Cytochrome P450
Type
Natural Products
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/r-6-7-dihydroxybergamottin.html
Solubility
10 mM in DMSO
Smiles
O=C1C=CC2=C(OC/C=C(C)/CC[C@@H](O)C(C)(O)C)C3=C(OC=C3)C=C2O1
Molecular Formula
C21H24O6
Molecular Weight
372.41
References & Citations
[1]Rebeca Santes-Palacios, et al. Inhibition of human and rat CYP1A1 enzyme by grapefruit juice compounds. Toxicol Lett. 2016 Sep 6:258:267-275.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported
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