Oleandomycin
Oleandomycin is a macrolide antibiotic structurally closely related to Erythromycin. Oleandomycin is similar to Erythromycin with antimicrobial activity. Oleandomycin inhibits protein synthesis by interference with translation of activated amino acids to nascent peptide chains on the ribosomes[1][2].
Product Specifications
CAS Number
3922-90-5
UNSPSC
12352005
Target
Antibiotic; Bacterial
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/Oleandomycin.html
Purity
99.84
Solubility
DMSO : 100 mg/mL (ultrasonic) |H2O : 12.5 mg/mL (ultrasonic)
Smiles
O=C1[C@H](C)[C@@H](O)[C@@H](C)[C@@H](C)OC([C@H](C)[C@@H](O[C@]2([H])O[C@@H](C)[C@H](O)[C@@H](OC)C2)[C@H](C)[C@@H](O[C@@]3([H])[C@H](O)[C@@H](N(C)C)C[C@@H](C)O3)[C@@H](C)C[C@@]14CO4)=O
Molecular Formula
C35H61NO12
Molecular Weight
687.86
References & Citations
[1]Vilches C, et al. Role of glycosylation and deglycosylation in biosynthesis of and resistance to oleandomycin in the producer organism, Streptomyces antibioticus. J Bacteriol. 1992 Jan;174 (1) :161-5.|[2]Semenitz E, et al. The antibacterial activity of oleandomycin and erythromycin--a comparative investigation using microcalorimetry and MIC determination. J Antimicrob Chemother. 1978 Sep;4 (5) :455-7.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Phase 4
Isoform
Macrolide
Available Sizes
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