Dopamine (hydrochloride)

Dopamine hydrochloride (ASL279) is a catecholamine neurotransmitter that is produced in the substantia nigra, ventral tegmental area, and hypothalamus of the brain. Dopamine hydrochloride (ASL279) plays several important roles in the brain and body[1]. Dopamine hydrochloride (ASL279) acts through D2 dopamine receptors to induce endocytosis of VEGFR2, which is critical for promoting angiogenesis[1].

Product Specifications

CAS Number

[62-31-7]

Product Name Alternative

ASL279

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Dopamine Receptor; Endogenous Metabolite; Ferroptosis

Type

Natural Products

Related Pathways

Apoptosis; GPCR/G Protein; Metabolic Enzyme/Protease; Neuronal Signaling

Applications

Neuroscience-Neurodegeneration

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/Dopamine-hydrochloride.html

Concentration

10mM

Purity

99.79

Solubility

DMSO : 50 mg/mL (ultrasonic) |H2O : ≥ 50 mg/mL

Smiles

OC1=CC=C(CCN)C=C1O.Cl

Molecular Formula

C8H12ClNO2

Molecular Weight

189.64

Precautions

H302, H315, H319, H335

References & Citations

[1]Juárez Olguín H, et al. The Role of Dopamine and Its Dysfunction as a Consequence of Oxidative Stress. Oxid Med Cell Longev. 2016;2016:9730467.|[2]Basu S, et al. The neurotransmitter dopamine inhibits angiogenesis induced by vascular permeability factor/vascular endothelial growth factor. Nat Med. 2001 May;7 (5) :569-74.