PE-Labeled Monoclonal Anti-B2M Antibody, Mouse IgG2b (0.03% Proclin)
PE-Labeled Monoclonal Anti-B2M Antibody, Mouse IgG2b is a mouse monoclonal antibody recombinantly expressed from human 293 cells (HEK293), which provides higher batch consistency and long term security of supply.
Product Specifications
Background
Beta-2-microglobulin (B2M) is a component of the class I major histocompatibility complex (MHC) and involved in the presentation of peptide antigens to the immune system. B2M consists of two β sheets joined by a disulfide bond, which could form amyloid fibrils in some pathological conditions. Increasing evidence has indicated that B2M gene alterations in tumor cells may lower the efficacy of T-cell based immunotherapies by hampering MHC class I-mediated tumor antigen presentation and avoiding T cell recognition.
Host
HEK293
Target
B2M
Conjugation
PE Labeled
Tag
Mouse IgG2b | Mouse kappa
Applications
Flow Cytometry (Evaluation of an epitope within the extracellular domain of human B2M protein) .
Stability
● -20°C to -70°C for 24 months in lyophilized state; ● -70°C for 12 months after reconstitution. ● 2-8 °C for 12 months after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower. Please protect from light and avoid repeated freeze-thaw cycles.
Format
Powder
Buffer
PBS, pH7.4,0.2% BSA, 0.03% Proclin300
Additives
Trehalose
Shipping Conditions
RT
Storage Conditions
-20°C, aviod light
Package Size
200tests*1
Product Datasheet
Https://www.acrobiosystems.com/static/main/products/pdf/ds/B2M-PM614c.pdf
Species
Mouse
CAS Number
9007-83-4
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