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CD58 Recombinant Rabbit Monoclonal Antibody [PSH02-74]

This gene encodes a member of the immunoglobulin superfamily. The encoded protein is a ligand of the T lymphocyte CD2 protein, and functions in adhesion and activation of T lymphocytes. The protein is localized to the plasma membrane. Alternatively spliced transcript variants have been described. Ligand of the T-lymphocyte CD2 glycoprotein. This interaction is important in mediating thymocyte interactions with thymic epithelial cells, antigen-independent and -dependent interactions of T-lymphocytes with target cells and antigen-presenting cells and the T-lymphocyte rosetting with erythrocytes. In addition, the LFA-3/CD2 interaction may prime response by both the CD2+ and LFA-3+ cells.

Product Specifications

Product Name Alternative

AG3 antibody CD58 antibody CD58 antigen (lymphocyte function associated antigen 3)1 antibody CD58 antigen antibody CD58 antigen, (lymphocyte function associated antigen 3) antibody CD58 molecule antibody FLJ23181 antibody FLJ43722 antibody LFA 3 antibody LFA-3 antibody LFA3 antibody LFA3_HUMAN antibody Lymphocyte Function Associated Antigen Type 3 antibody Lymphocyte function-associated antigen 3 antibody Surface glycoprotein LFA 3 antibody Surface glycoprotein LFA-3 antibody

Abbreviation

Lymphocyte function-associated antigen 3 Ag3 Surface glycoprotein LFA-3 CD58 LFA3

Swiss Prot

P19256 Human

Cellular Locus

Cell membrane.

Host

Rabbit

Species Reactivity

Human

Immunogen

Recombinant protein within human CD58 aa 29-215 (Extracellular).

Isotype

IgG

Clone

PSH02-74

Conjugation

Non-conjugated

Type

Recombinant Rabbit monoclonal Antibody

Applications

WB, FC

Positive Control

HeLa cell lysate, Raji cell lysate, Jurkat cell lysate, K-562 cell lysate, HUVEC cell lysate, HT-29 cell lysate, TF-1 cell lysate, MCF7 cell lysate, human peripheral blood lymphocytes.

Concentration

1 mg/mL

Dilution

WB: 1:1,000 ;FC: 1:1,000

Purity

Protein A affinity purified.

Form

Liquid

Buffer

PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

Molecular Weight

Predicted band size: 28 kDa

Storage Conditions

Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.

Recombinant Antibody

Yes

CAS Number

9000-83-3

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