Trimethyloctadecylammonium (bromide)

Trimethyloctadecylammonium bromide is an inhibitor of dynamin, with an IC50 value of 1.9 μM for dynamin I. Trimethyloctadecylammonium bromide exhibits antibacterial activity against Staphylococcus aureus[1][2].

Product Specifications

CAS Number

[1120-02-1]

UNSPSC

12352211

Hazard Statement

H302, H315, H317, H318, H410

Target

Dynamin

Type

Reference compound

Related Pathways

Cytoskeleton

Applications

COVID-19-immunoregulation

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/trimethyloctadecylammonium-bromide.html

Purity

99.67

Solubility

DMSO : 10 mg/mL (ultrasonic)

Smiles

CCCCCCCCCCCCCCCCCC[N+](C)(C)C.[Br-]

Molecular Formula

C21H46BrN

Molecular Weight

392.51

Precautions

H302, H315, H317, H318, H410

References & Citations

[1]Quan A, et al. Myristyl trimethyl ammonium bromide and octadecyl trimethyl ammonium bromide are surface-active small molecule dynamin inhibitors that block endocytosis mediated by dynamin I or dynamin II. Mol Pharmacol. 2007 Dec;72 (6) :1425-39. |[2]Baley GJ, et al. Bactericidal properties of quaternary ammonium compounds in dispersed systems. J Pharm Sci. 1977 May;66 (5) :696-9.