Glucose oxidase

Glucose oxidase is used in the food and beverage industry as a preservative and stabilizer and is commonly derived from the fungus Aspergillus niger. Glucose oxidase can react with intracellular glucose and oxygen (O2) to produce hydrogen peroxide (H2O2) and gluconic acid, which can cut off the nutrition source of cancer cells and consequently inhibit their proliferation[1][2][3].

Product Specifications

CAS Number

[9001-37-0]

UNSPSC

12352204

Hazard Statement

H334

Target

Endogenous Metabolite

Type

Enzyme

Related Pathways

Metabolic Enzyme/Protease

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/glucose-oxidase.html

Purity

Solubility

H2O : 50 mg/mL (ultrasonic)

Smiles

[Glucoseoxidase]

Precautions

H334

References & Citations

[1]Konishi T, et al. Safety evaluation of glucose oxidase from Penicillium chrysogenum [published correction appears in Regul Toxicol Pharmacol. 2013 Aug;66 (3) :300]. Regul Toxicol Pharmacol. 2013;66 (1) :13-23. |[2]Leskovac V, et al. Glucose oxidase from Aspergillus niger: the mechanism of action with molecular oxygen, quinones, and one-electron acceptors. Int J Biochem Cell Biol. 2005;37 (4) :731-750. |[3]Wang M, et al. Recent Advances in Glucose-Oxidase-Based Nanocomposites for Tumor Therapy. Small. 2019;15 (51) :e1903895. |[4]Khatami SH, et al. Glucose oxidase: Applications, sources, and recombinant production [published online ahead of print, 2021 Apr 11]. Biotechnol Appl Biochem. 2021;10.1002/bab.2165.