1,3-Diphenylguanidine

1,3-Diphenylguanidine is a widely used accelerator in rubber vulcanization. 1,3-Diphenylguanidine increases ROS activity and decreases SOD and CAT activity. 1,3-Diphenylguanidine accelerates the vulcanization process. 1,3-Diphenylguanidine impairs the reproduction and growth of Moina macrocopa[1] [2] [3] .

Product Specifications

CAS Number

[102-06-7]

UNSPSC

12352005

Hazard Statement

H301, H315, H319, H335, H361, H411

Target

Biochemical Assay Reagents; Reactive Oxygen Species (ROS) ; SOD

Type

Reference compound

Related Pathways

Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB; Others

Field of Research

Endocrinology

Assay Protocol

https://www.medchemexpress.com/1-3-diphenylguanidine.html

Concentration

10mM

Purity

99.76

Solubility

DMSO : ≥ 100 mg/mL

Smiles

N=C(NC1=CC=CC=C1)NC2=CC=CC=C2

Molecular Formula

C13H13N3

Molecular Weight

211.27

Precautions

H301, H315, H319, H335, H361, H411

References & Citations

[1]Ann Pontén, et al. Occupational allergic contact dermatitis caused by sterile non-latex protective gloves: clinical investigation and chemical analyses. Contact Dermatitis. 2013 Feb;68 (2) :103-10|[2]Yoganandham S T, et al. Assessment on acute and multigenerational toxicity of 1, 3-diphenylguanidine (DPG) on freshwater water fleas (Moina macrocopa) : Developmental, reproductive and oxidative stress effects. Environmental Chemistry and Ecotoxicology, 2025, 7: 27-38. |[3]Koëter HB, et al. Effect of oral administration of 1,3-diphenylguanidine on sperm morphology and male fertility in mice. Toxicology. 1992;71 (1-2) :173-9.