(S) -Thalidomide-NH-cyclohexane-NH-Ph-NH2
(S) -Thalidomide-NH-cyclohexane-NH-Ph-NH2 (Compound C63) is the E3 ligase + linker of PROTAC, which contains Thalidomide-based cereblon ligand and 1 linker and can be used for synthesis PROTAC[1].
Product Specifications
UNSPSC
12352005
Target
E3 Ligase Ligand-Linker Conjugates
Type
Reference compound
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/s-thalidomide-nh-cyclohexane-nh-ph-nh2.html
Smiles
O=C(C1=CC=CC(N[C@@H]2CCC[C@@H](NC3=CC(N)=CC=C3)C2)=C1C4=O)N4[C@@H]5C(NC(CC5)=O)=O
Molecular Formula
C25H27N5O4
Molecular Weight
461.51
References & Citations
[1]Guangliang Yu, et al. Medicine for treating human tumor by eRF3a targeting protein degradation mechanism. CN117801051A 2024-04-02.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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