Des-Arg9-[Leu8]-Bradykinin

<strong>Des-Arg9-[Leu8]-Bradykinin</strong> <strong>Catalog number:</strong> MDP0422 <strong>CAS Number: </strong>86933-74-6 <strong>Sequence: </strong>Arg-Pro-Pro-Gly-Phe-Ser-Pro-Leu . AcOH . 3H2O <strong>Amount:</strong> 5 mg <strong>Molecular Weight:</strong> 870 g/mol <strong>Supplied as:</strong> Powder <strong>Applications:</strong> molecular tool for various biochemical applications <strong>Storage:</strong> -20 °C <strong>WARNING:</strong> For in vitro Research Use Only. NOT for use on humans or animals. <strong>Grade:</strong> Biotechnology grade. All products are highly pure. <strong>References:</strong> 1: Farias NC, Feres T, Paiva AC, Paiva TB. Lys-[Leu8,des-Arg9]-bradykinin blocks lipopolysaccharide-induced SHR aorta hyperpolarization by inhibition of Ca(++)- and ATP-dependent K+ channels Eur J Pharmacol. 2004 Sep 13;498(1-3):163-9. 2: Rupniak NM, Boyce S, Webb JK, Williams AR, Carlson EJ, Hill RG, Borkowski JA, Hess JF. Effects of the bradykinin B1 receptor antagonist des-Arg9[Leu8]bradykinin and genetic disruption of the B2 receptor on nociception in rats and mice Pain. 1997 May;71(1):89-97. 3: Kaygısız Z, Kaygısız B, Kılınç E. The effect of Des-Arg9-bradykinin and bradykinin-potentiating peptide C on isolated rat hearts Acta Physiol Hung. 2013 Sep;100(3):280-8. 4: Hu DE, Fan TP. [Leu8]des-Arg9-bradykinin inhibits the angiogenic effect of bradykinin and interleukin-1 in rats Br J Pharmacol. 1993 May;109(1):14-7. 5: Eric J, Bkaily G, Bkaily GB, Volkov L, Gabra BH, Sirois P. Des-Arg9-bradykinin increases intracellular Ca2+ in bronchoalveolar eosinophils from ovalbumin-sensitized and -challenged mice Eur J Pharmacol. 2003 Aug 15;475(1-3):129-37. 6: Odya CE, Carlin RJ, Yapa RD, Soltani-Tehrani B. Immunoassays for des-Arg9-bradykinin J Immunoassay. 1993 Dec;14(4):227-40. 7: Alikhani M, Javadi A, Aalikhani M. Des-Arg9 bradykinin and bradykinin potentially trigger cytokine storm in patients with COVID-19 Iran J Immunol. 2021 Mar;18(1):93-94. 8: Cabrini DA, Calixto JB. Characterization of des-Arg9-bradykinin-induced contraction in guinea-pig gallbladder in vitro Eur J Pharmacol. 1997 Jul 16;331(1):31-8. 9: Marsh KA, Hill SJ. Des-Arg9-bradykinin-induced increases in intracellular calcium ion concentration in single bovine tracheal smooth muscle cells Br J Pharmacol. 1994 Jul;112(3):934-8. <a href="https://pubmed.ncbi.nlm.nih.gov/3013204">10: Sheikh IA, Kaplan AP. Studies of the digestion of bradykinin, Lys-bradykinin, and des-Arg9-bradykinin by angiotensin converting enzyme Biochem Pharmacol. 1986 Jun 15;35(12):1951-6. </a> <br><strong>Products Related to Des-Arg9-[Leu8]-Bradykinin can be found at</strong> <a href="https://moleculardepot.com/product-category/Peptides/"> Peptides</a>