Menadione

Menadione is a naphthoquinone that is converted into active vitamin K2 in the body. Menadione is a potential anticancer agent and radiosensitizer[1].

Product Specifications

CAS Number

[58-27-5]

Product Name Alternative

Vitamin K3

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H334, H335, H410

Target

Endogenous Metabolite

Type

Natural Products

Related Pathways

Metabolic Enzyme/Protease

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/Menadione.html

Purity

99.82

Solubility

DMSO : 125 mg/mL (ultrasonic) |Ethanol : 9.09 mg/mL (ultrasonic)

Smiles

O=C1C(C)=CC(C2=C1C=CC=C2)=O

Molecular Formula

C11H8O2

Molecular Weight

172.18

Precautions

H302, H315, H319, H334, H335, H410

References & Citations

[1]Chiou TJ, et al. Cardiac and renal toxicity of menadione in rat. Toxicology. 1997 Dec 31;124 (3) :193-202. |[2]Sata N, et al. Menadione induces both necrosis and apoptosis in rat pancreatic acinar AR4-2J cells. Free Radic Biol Med. 1997;23 (6) :844-50.