Macitentan (n-butyl analogue)
Macitentan n-butyl analogue is a n-butyl analogue of Macitentan. Macitentan is an orally active, non-peptide dual endothelin ETA and ETB receptor antagonist for the potential treatment of idiopathic pulmonary fibrosis (IPF) and pulmonary arterial hypertension (PAH) .
Product Specifications
CAS Number
556797-16-1
UNSPSC
12352005
Target
Endothelin Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein
Applications
COVID-19-immunoregulation
Field of Research
Cardiovascular Disease; Endocrinology
Assay Protocol
https://www.medchemexpress.com/Macitentan-n-butyl-analogue.html
Purity
99.35
Solubility
DMSO : 125 mg/mL (ultrasonic)
Smiles
BrC1=CN=C(OCCOC2=C(C3=CC=C(Br)C=C3)C(NS(CCCC)(=O)=O)=NC=N2)N=C1
Molecular Formula
C20H21Br2N5O4S
Molecular Weight
587.28
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
ETA; ETB
Available Sizes
Frequently Asked Questions
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