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Macitentan (n-butyl analogue)

Macitentan n-butyl analogue is a n-butyl analogue of Macitentan. Macitentan is an orally active, non-peptide dual endothelin ETA and ETB receptor antagonist for the potential treatment of idiopathic pulmonary fibrosis (IPF) and pulmonary arterial hypertension (PAH) .

Product Specifications

CAS Number

556797-16-1

UNSPSC

12352005

Target

Endothelin Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein

Applications

COVID-19-immunoregulation

Field of Research

Cardiovascular Disease; Endocrinology

Assay Protocol

https://www.medchemexpress.com/Macitentan-n-butyl-analogue.html

Purity

99.35

Solubility

DMSO : 125 mg/mL (ultrasonic)

Smiles

BrC1=CN=C(OCCOC2=C(C3=CC=C(Br)C=C3)C(NS(CCCC)(=O)=O)=NC=N2)N=C1

Molecular Formula

C20H21Br2N5O4S

Molecular Weight

587.28

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

ETA; ETB

Available Sizes

Frequently Asked Questions

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