JH-X-119-01 (hydrochloride)
Product Specifications
UNSPSC Description
JH-X-119-01 hydrochloride is a potent and selective interleukin-1 receptor-associated kinases 1 (IRAK1) inhibitor. JH-X-119-01 hydrochloride ameliorates LPS-induced sepsis in mice[1].
Target Antigen
IRAK
Type
Reference compound
Related Pathways
Immunology/Inflammation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/JH-X-119-01_hydrochloride.html
Purity
99.14
Solubility
DMSO : 50 mg/mL (ultrasonic)|H2O : < 0.1 mg/mL (ultrasonic;warming;heat to 60°C)
Smiles
O=C(C=C)NC1=CC=CC(C(NC2=CC=C(NC(C3=NC(C4=CC=NN4)=CC=C3)=O)C=C2)=O)=C1.Cl
Molecular Weight
488.93
References & Citations
[1]Bin Pan, et al. Selective inhibition of interleukin-1 receptor-associated kinase 1 ameliorates lipopolysaccharide-induced sepsis in mice. Int Immunopharmacol. 2020 Aug;85:106597.Emerg Microbes Infect. 2024 Jan 2:2300452.|University of Louisville. 2023 May 24.|JCI Insight. 2022 Jul 8;7(13):e149825.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-103017/JH-X-119-01-hydrochloride-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-103017/JH-X-119-01-hydrochloride-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
2591344-30-6
Available Sizes
Curated Selection
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