Isocitrate dehydrogenase, Porcine heart

Isocitrate dehydrogenase, Porcine heart (ICDH) is a citric acid or tricarboxylic acid cycle enzyme, is often used in biochemical studies. Isocitrate dehydrogenase catalyzes the oxidative decarboxylation of isocitrate to α-ketoglutarate and reduces NAD (P) + to NAD (P) H, it plays important roles in cellular metabolism[1].

Product Specifications

CAS Number

[9028-48-2]

Product Name Alternative

ICDH; IDH

UNSPSC

12352204

Hazard Statement

H334

Target

Isocitrate Dehydrogenase (IDH)

Type

Enzyme

Related Pathways

Metabolic Enzyme/Protease

Applications

Metabolism-sugar/lipid metabolism

Field of Research

Metabolic Disease; Cancer

Assay Protocol

https://www.medchemexpress.com/isocitrate-dehydrogenase-porcine-heart.html

Solubility

10 mM in DMSO

Smiles

[Isocitratedehydrogenase,Porcineheart]

Precautions

P261-P284-P304+P340-P501

References & Citations

[1]Reitman ZJ, Yan H. Isocitrate dehydrogenase 1 and 2 mutations in cancer: alterations at a crossroads of cellular metabolism. J Natl Cancer Inst. 2010 Jul 7;102 (13) :932-41.