5 (6) -ROX

5 (6) -ROX (5 (6) -Carboxy-X-rhodamine) is a nucleic acid fluorescent label which can be used as a reference dye for real-time polymerase chain reaction (Em/Ex = 605/585 nm) [1].

Product Specifications

CAS Number

[198978-94-8]

Product Name Alternative

5 (6) -Carboxy-X-rhodamine

UNSPSC

12171500

Hazard Statement

H302, H315, H319, H335

Target

DNA Stain

Type

Dye Reagents

Related Pathways

Cell Cycle/DNA Damage

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/5_6_-ROX.html

Purity

98.50

Solubility

DMSO : 20 mg/mL (ultrasonic; warming; heat to 60°C)

Smiles

[O-]C(C1=CC(C(O)=O)=CC=C1C(C2=C(O3)C4=C5N(CCC4)CCCC5=C2)=C6C3=C(CCC7)C8=[N+]7CCCC8=C6)=O.[O-]C(C9=CC=C(C(O)=O)C=C9C(C%10=C(O%11)C%12=C%13N(CCC%12)CCCC%13=C%10)=C%14C%11=C(CCC%15)C%16=[N+]%15CCCC%16=C%14)=O

Molecular Formula

C33H30N2O5

Molecular Weight

534.60

Precautions

H302, H315, H319, H335

References & Citations

[1]Wang G, et al. Optimization of 6-carboxy-X-rhodamine concentration for real-time polymerase chain reaction using molecular beacon chemistry. Can J Microbiol. 2007 Mar;53 (3) :391-7.