Antiproliferative agent-35
Antiproliferative agent-35 (Compound 4) is an anticancer agent derivated from Esculetin (HY-N0284) . Antiproliferative agent-35 inhibits the proliferation of B16 and A549 cells, with IC50s of 13.2 and 9.2 μM resspectively[1].
Product Specifications
CAS Number
[82747-36-2]
UNSPSC
12352005
Hazard Statement
H302-H315-H319-H335
Target
Drug Derivative
Type
Reference compound
Related Pathways
Others
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/antiproliferative-agent-35.html
Solubility
10 mM in DMSO
Smiles
C1=C2C(=CC(=O)OC2=CC(=C1O)O)C(F)(F)F
Molecular Formula
C10H5F3O4
Molecular Weight
246.14
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
References & Citations
[1]Ping Wang, et al. Design, synthesis and biological evaluation of esculetin derivatives as anti-tumour agents. RSC Advances. Issue 66, 2015
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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