Cotosudil
Cotosudil is a ROCK kinase inhibitor, which can be used for glaucoma or ocular hypertension research[1].
Product Specifications
CAS Number
[1258833-31-6]
UNSPSC
12352005
Target
ROCK
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage; Cytoskeleton; Stem Cell/Wnt; TGF-beta/Smad
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Endocrinology
Assay Protocol
https://www.medchemexpress.com/cotosudil.html
Purity
98.19
Solubility
DMSO : 50 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
O=S(C1=CC2=C(C=NC=C2)C=C1)(N3[C@@H](CNCCCC3)C)=O
Molecular Formula
C16H21N3O2S
Molecular Weight
319.42
References & Citations
[1]IYoshihiro Inoue, et al. Prophylactic or therapeutic agent for glaucoma or ocular hypertension. JP2013035802A.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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