Cotosudil

Cotosudil is a ROCK kinase inhibitor, which can be used for glaucoma or ocular hypertension research[1].

Product Specifications

CAS Number

[1258833-31-6]

UNSPSC

12352005

Target

ROCK

Type

Reference compound

Related Pathways

Cell Cycle/DNA Damage; Cytoskeleton; Stem Cell/Wnt; TGF-beta/Smad

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Endocrinology

Assay Protocol

https://www.medchemexpress.com/cotosudil.html

Purity

98.19

Solubility

DMSO : 50 mg/mL (ultrasonic; warming; heat to 60°C)

Smiles

O=S(C1=CC2=C(C=NC=C2)C=C1)(N3[C@@H](CNCCCC3)C)=O

Molecular Formula

C16H21N3O2S

Molecular Weight

319.42

References & Citations

[1]IYoshihiro Inoue, et al. Prophylactic or therapeutic agent for glaucoma or ocular hypertension. JP2013035802A.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

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