Withaphysalin D
Product Specifications
UNSPSC Description
Withaphysalin D is a selective antagonist against the N-methyl-D-aspartate receptor (NMDAR) containing GluN2B. Withaphysalin D can be isolated from water lilies and has neuroprotective properties. Withaphysalin D is able to cross the blood-brain barrier[1].
Target Antigen
iGluR
Type
Natural Products
Related Pathways
Membrane Transporter/Ion Channel;Neuronal Signaling
Applications
Neuroscience-Neurodegeneration
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/withaphysalin-d.html
Solubility
10 mM in DMSO
Smiles
CC(C[C@@H]([C@@]1(OC([C@]23CC[C@@H]4[C@]5(C(CC=CC5=CC[C@H]4[C@@]2(CC[C@@H]31)O)=O)C)=O)C)O6)=C(C)C6=O
Molecular Weight
466.57
References & Citations
[1]Kumar G,et al. Exploring neuroprotective potential of Withania somnifera phytochemicals by inhibition of GluN2B-containing NMDA receptors: An in silico study. Med Hypotheses. 2016 Jul;92:35-43.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-N11061/Withaphysalin-D-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-N11061/
Clinical Information
No Development Reported
CAS Number
91599-21-2
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