G6PI 325-339 (human) (hydrochloride)
G6PI 325-339 (human) hydrochloride is an efficient inducer of arthritis in B10.Q mice. G6PI 325-339 (human) hydrochloride primes Th1 and Th17 cells cross-reacted with the murine G6PI protein. G6PI 325-339 (human) hydrochloride induces arthritis model operating through a T and B cell-dependent pathway but without antibody effector mechanisms[1].
Product Specifications
Product Name Alternative
HG6PI (325-339) (hydrochloride)
UNSPSC
12352209
Target
Others
Type
Peptides
Related Pathways
Others
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/g6pi-325-339-human-hydrochloride.html
Solubility
10 mM in DMSO
Smiles
OC(C=C1)=CC=C1C[C@@H](C(N[C@@H]([C@@H](C)CC)C(N[C@@H](CC(N)=O)C(N[C@@H](CS)C(N[C@H](C(NCC(N[C@@H](CS)C(N[C@@H](CCC(O)=O)C(N[C@@H]([C@H](O)C)C(N[C@H](C(N[C@@H](C)C(N[C@@H](CCSC)C(N[C@H](C(O)=O)CC(C)C)=O)=O)=O)CC2=CN=CN2)=O)=O)=O)=O)=O)CC3=CC=CC=C3)=O)=O)=O)=O)NC([C@@H](NC([C@@H](N)[C@@H](C)CC)=O)CC4=CNC5=CC=CC=C45)=O.[H]Cl.[x]
Molecular Formula
C82H117N19O21S3.xHCl
Molecular Weight
1801.12 (free base)
References & Citations
[1]Angela Pizzolla, et al. A glucose-6-phosphate isomerase peptide induces T and B cell-dependent chronic arthritis in C57BL/10 mice: arthritis without reactive oxygen species and complement. Am J Pathol. 2013 Oct;183 (4) :1144-1155.|[2]Bruns L, et al. Immunization with an immunodominant self-peptide derived from glucose-6-phosphate isomerase induces arthritis in DBA/1 mice. Arthritis Res Ther. 2009;11 (4) :R117.
Shipping Conditions
Room temperature
Scientific Category
Peptides
Clinical Information
No Development Reported
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog