CUMI-101
CUMI-101 (compound 8) is a 5-HT1AR agonist (Ki=0.15 nM) with an EC50 of 0.1 nM in the [35S]GTPγS binding assay. CUMI-101 can be used in the research of neurological diseases[1].
Product Specifications
CAS Number
179756-61-7
UNSPSC
12352005
Target
5-HT Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/cumi-101.html
Smiles
O=C(N(N=CC1=O)CCCCN2CCN(CC2)C3=CC=CC=C3OC)N1C
Molecular Formula
C19H27N5O3
Molecular Weight
373.45
References & Citations
[1]Kumar J S D, et al. Synthesis and evaluation of arylpiperazines derivatives of 3, 5-dioxo- (2H, 4H) -1, 2, 4-triazine as 5-HT1AR ligands[J]. Bioorganic & medicinal chemistry letters, 2014, 24 (19) : 4759-4762.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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