Antiflammin 2

Antiflammin 2 inhibits the synthesis of platelet-activating factor (PAF) with the IC50 of 100 nM[1].

Product Specifications

CAS Number

[118850-72-9]

UNSPSC

12352209

Target

Platelet-activating Factor Receptor (PAFR)

Type

Peptides

Related Pathways

GPCR/G Protein

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/antiflammin-2.html

Purity

99.50

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

N[C@@H](CC1=CN=CN1)C(N[C@@H](CC(O)=O)C(N[C@@H](CCSC)C(N[C@@H](CC(N)=O)C(N[C@@H](CCCCN)C(N[C@@H](C(C)C)C(N[C@@H](CC(C)C)C(N[C@@H](CC(O)=O)C(N[C@H](C(O)=O)CC(C)C)=O)=O)=O)=O)=O)=O)=O)=O

Molecular Formula

C46H77N13O15S

Molecular Weight

1084.25

References & Citations

[1]G Camussi, et al. Antiinflammatory peptides (antiflammins) inhibit synthesis of platelet-activating factor, neutrophil aggregation and chemotaxis, and intradermal inflammatory reactions. J Exp Med. 1990 Mar 1;171 (3) :913-27.