Pentifylline
Pentifylline is a vasodilator with anti-inflammatory activity. Pentifylline inhibits platelet aggregation and thromboxane A2 synthesis, reduces the release of free radicals, and decreases the production of type 1 collagen and laminin in fibroblasts. Pentifylline has the potential to be studied in acute ischemic stroke[1][2].
Product Specifications
CAS Number
1028-33-7
Product Name Alternative
1-Hexyltheobromine; Hexyltheobromine
UNSPSC
12352005
Hazard Statement
H315, H319, H335
Target
Collagen
Type
Reference compound
Related Pathways
Cytoskeleton
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/pentifylline.html
Purity
99.23
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
CCCCCCN1C(=O)C2=C(N=CN2C)N(C)C1=O
Molecular Formula
C13H20N4O2
Molecular Weight
264.32
Precautions
H315, H319, H335
References & Citations
[1]Bath PM, et al. Pentoxifylline, propentofylline and pentifylline for acute ischaemic stroke. Cochrane Database Syst Rev. 2004; (3) :CD000162.|[2]Saika S, et al. Pentoxifylline and pentifylline inhibit proliferation of human Tenon's capsule fibroblasts and production of type-I collagen and laminin in vitro. Ophthalmic Res. 1996;28 (3) :165-70.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Phase 4
Available Sizes
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