Pentifylline

Pentifylline is a vasodilator with anti-inflammatory activity. Pentifylline inhibits platelet aggregation and thromboxane A2 synthesis, reduces the release of free radicals, and decreases the production of type 1 collagen and laminin in fibroblasts. Pentifylline has the potential to be studied in acute ischemic stroke[1][2].

Product Specifications

CAS Number

[1028-33-7]

Product Name Alternative

1-Hexyltheobromine; Hexyltheobromine

UNSPSC

12352005

Hazard Statement

H315, H319, H335

Target

Collagen

Type

Reference compound

Related Pathways

Cytoskeleton

Applications

Neuroscience-Neuromodulation

Field of Research

Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/pentifylline.html

Purity

99.23

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

CCCCCCN1C(=O)C2=C(N=CN2C)N(C)C1=O

Molecular Formula

C13H20N4O2

Molecular Weight

264.32

Precautions

H315, H319, H335

References & Citations

[1]Bath PM, et al. Pentoxifylline, propentofylline and pentifylline for acute ischaemic stroke. Cochrane Database Syst Rev. 2004; (3) :CD000162.|[2]Saika S, et al. Pentoxifylline and pentifylline inhibit proliferation of human Tenon's capsule fibroblasts and production of type-I collagen and laminin in vitro. Ophthalmic Res. 1996;28 (3) :165-70.