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Pentifylline

Pentifylline is a vasodilator with anti-inflammatory activity. Pentifylline inhibits platelet aggregation and thromboxane A2 synthesis, reduces the release of free radicals, and decreases the production of type 1 collagen and laminin in fibroblasts. Pentifylline has the potential to be studied in acute ischemic stroke[1][2].

Product Specifications

CAS Number

[1028-33-7]

Product Name Alternative

1-Hexyltheobromine; Hexyltheobromine

UNSPSC

12352005

Hazard Statement

H315, H319, H335

Target

Collagen

Type

Reference compound

Related Pathways

Cytoskeleton

Applications

Neuroscience-Neuromodulation

Field of Research

Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/pentifylline.html

Purity

99.23

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

CCCCCCN1C(=O)C2=C(N=CN2C)N(C)C1=O

Molecular Formula

C13H20N4O2

Molecular Weight

264.32

Precautions

H315, H319, H335

References & Citations

[1]Bath PM, et al. Pentoxifylline, propentofylline and pentifylline for acute ischaemic stroke. Cochrane Database Syst Rev. 2004; (3) :CD000162.|[2]Saika S, et al. Pentoxifylline and pentifylline inhibit proliferation of human Tenon's capsule fibroblasts and production of type-I collagen and laminin in vitro. Ophthalmic Res. 1996;28 (3) :165-70.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-W273690/Pentifylline-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-W273690/Pentifylline-SDS-MedChemExpress.pdf

Scientific Category

Reference compound1

Clinical Information

Phase 4

Available Sizes

Curated Selection

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