5,6-DCl-cBIMP
5,6-DCl-cBIMP, a cyclic adenosine monophosphate analog, can act as an agonist of PDE2 and significantly enhance the cAMP and cGMP hydrolytic activities of PDE2[1][2].
Product Specifications
CAS Number
129693-10-3
UNSPSC
12352005
Target
Phosphodiesterase (PDE)
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/5-6-dcl-cbimp.html
Smiles
O[C@@H]1[C@H](O2)[C@@H](COP2(O)=O)O[C@H]1N(C=N3)C4=C3C=C(Cl)C(Cl)=C4
Molecular Formula
C12H11Cl2N2O6P
Molecular Weight
381.11
References & Citations
[1]McMartin L, et al. Functional analysis of desensitization of the β‐adrenoceptor signalling pathway in rat cardiac tissues following chronic isoprenaline infusion[J]. British journal of pharmacology, 1999, 127 (4) : 1012-1020.|[2]Jäger R, et al. Activation of PDE2 and PDE5 by specific GAF ligands: delayed activation of PDE5[J]. British journal of pharmacology, 2010, 161 (7) : 1645-1660.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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