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Cryopyrin Rabbit Polyclonal Antibody

Cryopyrin Rabbit Polyclonal Antibody is an unconjugated antibody that specifically recognizes Cryopyrin. Generated against a KLH conjugated synthetic peptide derived from human Cryopyrin. The peptide is available as orb374803. The suitable applications for this antibody are IHC-P.

Product Specifications

Product Name Alternative

Anti AGTAVPRL antibody, anti C1orf7 antibody, anti Caterpiller protein 1.1 antibody, anti CIAS 1 antibody, anti CIAS1 antibody, anti FCAS antibody, anti FCU antibody, anti MWS antibody, anti NACHT antibody, anti NALP3 antibody, anti NALP 3 antibody, anti NALP-3 antibody, anti NLRP3 antibody, anti PYPAF 1 antibody, anti PYPAF1 antibody, anti PYRIN containing APAF1 like protein 1 antibody

UniProt

Q8R4B8, Q96P20

Immunogen

KLH conjugated synthetic peptide derived from human Cryopyrin. Please contact us for the exact immunogen sequence. The peptide is available as orb374803.

Target

Cryopyrin

Clonality

Polyclonal

Conjugation

Unconjugated

Concentration

- 100 μg (in 200 μl) : 0.5 mg/ml- 200 μg (in 400 μl) : 0.5 mg/ml

Dilution

IHC-P: 1:100-1:500

Purity

Polyclonal antibodies are purified by peptide affinity chromatography

Form

10 mM PBS, 0.02% sodium azide

Molecular Weight

118 kDa

References & Citations

He, Wei et al. Microglial NLRP3 inflammasome activation mediates IL-1β release and contributes to central sensitization in a recurrent nitroglycerin-induced migraine model J Neuroinflammation, 16, 78 (2019), Wilson, C. Brad et al. Valproic acid effects in the hippocampus and prefrontal cortex in an animal model of post-traumatic stress disorder Behav Brain Res, 268, 72-80 (2014), He, Xue-Mei et al. Ellagic Acid Protects Dopamine Neurons via Inhibition of NLRP3 Inflammasome Activation in Microglia Oxid Med Cell Longev, 2020, 2963540 (2020), Wilson, C. Brad et al. Inflammation and oxidative stress are elevated in the brain, blood, and adrenal glands during the progression of post-traumatic stress disorder in a predator exposure animal model PLoS One, 8, e76146 (2013)

Pubmed id

30971286, 24675160, 33294118, 24130763

Storage Conditions

Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

Notes

For research use only.

Tested Applications

IHC-P

NCBI Accession Number

001073289, 21, 001079821, 11

Host or Source

Rabbit

Isotype

IgG

Entrez

114548

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