LX-3
LX-3 is a selective activator of the p38 MAPK signaling pathway and activates EGFP reporter genes that are silenced by DNA methylation, such as TNF, EGR1, LY6K, and ISG20[1].
Product Specifications
CAS Number
380645-50-1
UNSPSC
12352005
Target
P38 MAPK
Type
Reference compound
Related Pathways
MAPK/ERK Pathway
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/lx-3.html
Purity
98.08
Solubility
DMSO : 50 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
BrC1=CC=C(C(CN2C3=NC(C4=CC=CS4)=NN3C5=CC=CC=C25)=O)C=C1
Molecular Formula
C20H13BrN4OS
Molecular Weight
437.31
References & Citations
[1]Li X, et al., Small molecules capable of activating DNA methylation-repressed genes targeted by the p38 mitogen-activated protein kinase pathway. J Biol Chem. 2018 May 11;293 (19) :7423-7436.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
TL704846V 500 µL Each
Nosip Rat shRNA Lentiviral Particle (Locus ID 292894)
Sign In for Pricing
View Details 
PA1569-APC 100 µg/Vial
Anti-Eph receptor B3/EPHB3 Antibody Picoband®, APC Conjugate
Sign In for Pricing
View Details 