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CXCR1 Rabbit Polyclonal Antibody

CXCR1 Rabbit Polyclonal Antibody is an unconjugated antibody that specifically recognizes CXCR1. Generated against a KLH conjugated synthetic peptide derived from human CXCR1. The peptide is available as orb12890. The suitable applications for this antibody are ICC, IF, IHC-P and WB.

Product Specifications

UniProt

Q810W6, P70612, P25024

Immunogen

KLH conjugated synthetic peptide derived from human CXCR1. Please contact us for the exact immunogen sequence. The peptide is available as orb12890.

Target

CXCR1

Clonality

Polyclonal

Conjugation

Unconjugated

Field of Research

Immunology & Inflammation

Concentration

- 100 μg (in 200 μl) : 0.5 mg/ml- 200 μg (in 400 μl) : 0.5 mg/ml

Dilution

WB: 1:100-800, IHC-P: 1:100-600, IF/ICC: 1:100-600

Purity

Polyclonal antibodies are purified by peptide affinity chromatography

Form

10 mM PBS, 0.02% sodium azide

Molecular Weight

40 kDa

References & Citations

Dutta, Puja et al. Regulation of Staphylococcus aureus-induced CXCR1 expression via inhibition of receptor mobilization and receptor shedding during dual receptor (TNFR1 and IL-1R) neutralization Immunol Res, 67, 241-260 (2019), Dutta, Puja et al. Neutralization of TNF-α and IL-1β Regulates CXCL8 Production through CXCL8/CXCR1 Axis in Macrophages during Staphylococcus aureus Infection Immunol. Invest., (2020), Bishayi, Biswadev et al. Expression of CXCR1 (interleukin-8 receptor) in murine macrophages after staphylococcus aureus infection and its possible implication on intracellular survival correlating with cytokines and bacterial anti-oxidant enzymes Inflammation, 38, 812-827 (2015), Nandi, Ajeya et al. Murine macrophage response from peritoneal cavity requires signals mediated by chemokine receptor CCR-2 during Staphylococcus aureus infection Immunol Res, 64, 213-232 (2016), Ajeya Nandi, Biswadev Bishayi A novel CCR-2/TLR-2 triggered signaling in murine peritoneal macrophages intensifies bacterial (Staphylococcus aureus) killing by reactive oxygen species through TNF-R1 Immunology Letters, 190, (2017), Ajeya Nandi, Biswadev Bishayi CCR-2 neutralization augments murine fresh BMC activation by Staphylococcus aureus via two distinct mechanisms: at the level of ROS production and cytokine response Innate Immunity, 23, 345 (2017)

Pubmed id

31290001, 32602757, 25129059, 26616292, 28736159, 28409543

Storage Conditions

Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

Notes

For research use only.

Tested Applications

ICC, IF, IHC-P, WB

NCBI Accession Number

000625

Host or Source

Rabbit

Isotype

IgG

Entrez

3577

Available Sizes

Frequently Asked Questions

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