P2Y6R antagonist 1
P2Y6R antagonist 1 (compound 5ab) is a selective, orally active P2Y6R antagonist with an IC50 value of 19.6 nM. P2Y6R antagonist 1 has anti-inflammatory activity[1].
Product Specifications
UNSPSC
12352005
Target
P2Y Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/p2y6r-antagonist-1.html
Concentration
10mM
Purity
99.94
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C(O)CCC(N1N=C(C2=CC=CN2)CC1C3=CC4=CC=CC=C4N=C3)=O
Molecular Formula
C20H18N4O3
Molecular Weight
362.38
References & Citations
[1]Zhao Y, et al. Discovery of a potent, Highly selective, and In vivo anti-inflammatory Efficacious, P2Y6R antagonist with a novel quinoline-pyrazole scaffold. Eur J Med Chem. 2024 Sep 23;279:116890.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
P2Y6 Receptor
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
![PAGE1 Mouse Monoclonal Antibody [Clone ID: OTI4A6]](https://cdn.genprice.uk/products/937/68dd18b9061270361e907d80/imageurl/cf805638.webp)
BNC041957-500 1x 500 µL
Filaggrin (Keratinocyte Differentiation Marker) (FLG/1957R), CF405S conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
![VAMP5 Mouse Monoclonal Antibody (HRP conjugated) [Clone ID: OTI7F2]](https://cdn.genprice.uk/products/937/68dd1b80061270361ea1e432/imageurl/ta808605bm.webp)
TA808605BM 100 µL
VAMP5 Mouse Monoclonal Antibody (HRP conjugated) [Clone ID: OTI7F2]
Sign In for Pricing
View Details 