LGB321
LGB321 is an inhibitor of PIM2-dependent multiple myeloma cell lines, effectively inhibiting proliferation and key signaling pathways such as mTOR-C1 and phosphorylation of BAD[1].
Product Specifications
CAS Number
[1210417-75-6]
UNSPSC
12352005
Target
MTOR
Type
Reference compound
Related Pathways
PI3K/Akt/mTOR
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/lgb321.html
Smiles
O=C(C1=NC(C2=C(F)C=CC=C2F)=C(F)C=C1)NC3=C(N4C[C@@H](N)[C@H](O)[C@@H](C)C4)C=CN=C3
Molecular Formula
C23H22F3N5O2
Molecular Weight
457.45
References & Citations
[1]Pan-PIM Kinase Inhibition Provides a Novel Therapy for Treating Hematologic Cancers
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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