LGB321
LGB321 is an inhibitor of PIM2-dependent multiple myeloma cell lines, effectively inhibiting proliferation and key signaling pathways such as mTOR-C1 and phosphorylation of BAD[1].
Product Specifications
CAS Number
[1210417-75-6]
UNSPSC
12352005
Target
MTOR
Type
Reference compound
Related Pathways
PI3K/Akt/mTOR
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/lgb321.html
Smiles
O=C(C1=NC(C2=C(F)C=CC=C2F)=C(F)C=C1)NC3=C(N4C[C@@H](N)[C@H](O)[C@@H](C)C4)C=CN=C3
Molecular Formula
C23H22F3N5O2
Molecular Weight
457.45
References & Citations
[1]Pan-PIM Kinase Inhibition Provides a Novel Therapy for Treating Hematologic Cancers
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
TA504606AM 100 µL
Carboxypeptidase A (CPA1) Mouse Monoclonal Antibody (Biotin conjugated) [Clone ID: OTI4E12]
Ask
View Details