Lamifiban (TFA)
Lamifiban TFA is a nonpeptide glycoprotein IIb/IIIa receptor and platelet aggregation antagonist. Lamifiban TFA in combination with thrombolytic therapy effectively restores coronary arterial patency. Lamifiban TFA is promising for research of acute coronary syndromes[1].
Product Specifications
CAS Number
[144412-50-0]
UNSPSC
12352005
Target
Integrin
Type
Reference compound
Related Pathways
Cytoskeleton
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/lamifiban-tfa.html
Smiles
OC(C(F)(F)F)=O.O=C(N1CCC(CC1)OCC(O)=O)[C@@H](NC(C2=CC=C(C=C2)C(N)=N)=O)CC3=CC=C(C=C3)O
Molecular Formula
C26H29F3N4O8
Molecular Weight
582.53
References & Citations
[1]Moliterno DJ, et al. Randomized, Placebo-Controlled Study of Lamifiban with Thrombolytic Therapy for the Treatment of Acute Myocardial Infarction: Rationale and Design for the Platelet Aggregation Receptor Antagonist Dose Investigation and Reperfusion Gain in Myocardial Infarction (PARADIGM) Study. J Thromb Thrombolysis. 1995;2 (3) :165-169.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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