VEGFR-2-IN-37
VEGFR-2-IN-37 (compound 12) is an inhibitor of VEGFR-2. The inhibition rate at 200 μM was approximately 56.9 μM. VEGFR-2-IN-37 is a potential inhibitor of human umbilical vein endothelial cell (HUVEC) proliferation[1].
Product Specifications
CAS Number
[298207-77-9]
UNSPSC
12352005
Hazard Statement
H302-H315-H319
Target
VEGFR
Type
Reference compound
Related Pathways
Protein Tyrosine Kinase/RTK
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/vegfr-2-in-37.html
Purity
99.11
Solubility
DMSO : 25 mg/mL (ultrasonic)
Smiles
O=C(C)C1=CC(OC2=NC=NC3=C2C(CCCC4)=C4S3)=CC=C1
Molecular Formula
C18H16N2O2S
Molecular Weight
324.40
Precautions
P264-P270-P280-P302+P352-P305+P351+P338-P330-P362+P364-P501
References & Citations
[1]Perspicace E, et al. Design, synthesis and biological evaluation of new classes of thieno[3,2-d]pyrimidinone and thieno[1,2,3]triazine as inhibitor of vascular endothelial growth factor receptor-2 (VEGFR-2) . Eur J Med Chem. 2013 May;63:765-81.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
