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VEGFR-2-IN-37

VEGFR-2-IN-37 (compound 12) is an inhibitor of VEGFR-2. The inhibition rate at 200 μM was approximately 56.9 μM. VEGFR-2-IN-37 is a potential inhibitor of human umbilical vein endothelial cell (HUVEC) proliferation[1].

Product Specifications

CAS Number

298207-77-9

UNSPSC

12352005

Hazard Statement

H302-H315-H319

Target

VEGFR

Type

Reference compound

Related Pathways

Protein Tyrosine Kinase/RTK

Applications

Cancer-Kinase/protease

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/vegfr-2-in-37.html

Purity

99.11

Solubility

DMSO : 25 mg/mL (ultrasonic)

Smiles

O=C(C)C1=CC(OC2=NC=NC3=C2C(CCCC4)=C4S3)=CC=C1

Molecular Formula

C18H16N2O2S

Molecular Weight

324.40

Precautions

P264-P270-P280-P302+P352-P305+P351+P338-P330-P362+P364-P501

References & Citations

[1]Perspicace E, et al. Design, synthesis and biological evaluation of new classes of thieno[3,2-d]pyrimidinone and thieno[1,2,3]triazine as inhibitor of vascular endothelial growth factor receptor-2 (VEGFR-2) . Eur J Med Chem. 2013 May;63:765-81.

Shipping Conditions

Room Temperature

Storage Conditions

4°C (Powder, protect from light)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

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