SPHINX
SPHINX is a selective SRPK1 inhibitor with an IC50 value of 0.58 μM. SPHINX effectively reduces Choroidal Neovascularization (CNV) in vivo. SPHINX can be used for the research of (age-related macular degenaration) AMD[1].
Product Specifications
CAS Number
848057-98-7
UNSPSC
12352005
Hazard Statement
H302-H315-H319-H335
Target
SRPK
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-Kinase/protease
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/sphinx.html
Purity
99.87
Solubility
DMSO : 50 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
O=C(C1=CC=C(C)O1)NC2=CC(C(F)(F)F)=CC=C2N3CCOCC3
Molecular Formula
C17H17F3N2O3
Molecular Weight
354.32
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
References & Citations
[1]Gammons MV, et al. Topical antiangiogenic SRPK1 inhibitors reduce choroidal neovascularization in rodent models of exudative AMD. Invest Ophthalmol Vis Sci. 2013 Sep 5;54 (9) :6052-62.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
LC426137 20 µg
LINC02877 (NM_001101337) Human Over-expression Lysate
Sign In for Pricing
View Details 
E-UNEL-M0055-01 5x 96 Tests
Uncoated Mouse CX3CL1 (Chemokine C-X3-C-Motif Ligand 1) ELISA Kit
Sign In for Pricing
View Details E-UNEL-M0055-02 15x 96 Tests
Uncoated Mouse CX3CL1 (Chemokine C-X3-C-Motif Ligand 1) ELISA Kit
Sign In for Pricing
View Details