FSB
Product Specifications
UNSPSC Description
FSB is a fluorescent dye that can be used to detect filamentous tau and to label human amyloid lesions with high sensitivity and specificity (excitation: 390 nm, emission: 520 nm)[1][2].
Target Antigen
Amyloid-β
Type
Dye Reagents
Related Pathways
Neuronal Signaling
Applications
Neuroscience-Neurodegeneration
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/fsb.html
Purity
99.5
Solubility
DMSO : 200 mg/mL (ultrasonic;warming)
Smiles
OC1=CC=C(/C=C/C2=CC=C(C(F)=C2)/C=C/C3=CC=C(C(C(O)=O)=C3)O)C=C1C(O)=O
Molecular Weight
420.39
References & Citations
[1]Velasco A, et al. Detection of filamentous tau inclusions by the fluorescent Congo red derivative FSB [(trans,trans)-1-fluoro-2,5-bis(3-hydroxycarbonyl-4-hydroxy)styrylbenzene]. FEBS Lett. 2008 Mar 19;582(6):901-6. |[2]Sato K, et al. Fluoro-substituted and 13C-labeled styrylbenzene derivatives for detecting brain amyloid plaques. Eur J Med Chem. 2004 Jul;39(7):573-8.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, sealed storage, away from moisture and light)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-D1494/FSB-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-D1494/FSB-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
760988-03-2
Available Sizes
Curated Selection
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