FSB

Product Specifications

CAS Number

[760988-03-2]

UNSPSC Description

FSB is a fluorescent dye that can be used to detect filamentous tau and to label human amyloid lesions with high sensitivity and specificity (excitation: 390 nm, emission: 520 nm)[1][2].

Target Antigen

Amyloid-β

Type

Dye Reagents

Related Pathways

Neuronal Signaling

Applications

Neuroscience-Neurodegeneration

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/fsb.html

Purity

99.5

Solubility

DMSO : 200 mg/mL (ultrasonic;warming)

Smiles

OC1=CC=C(/C=C/C2=CC=C(C(F)=C2)/C=C/C3=CC=C(C(C(O)=O)=C3)O)C=C1C(O)=O

Molecular Weight

420.39

References & Citations

[1]Velasco A, et al. Detection of filamentous tau inclusions by the fluorescent Congo red derivative FSB [(trans,trans)-1-fluoro-2,5-bis(3-hydroxycarbonyl-4-hydroxy)styrylbenzene]. FEBS Lett. 2008 Mar 19;582(6):901-6. |[2]Sato K, et al. Fluoro-substituted and 13C-labeled styrylbenzene derivatives for detecting brain amyloid plaques. Eur J Med Chem. 2004 Jul;39(7):573-8.