Alinidine
Alinidine (St-567) is a specific bradycardic agent. Alinidine reduces the slope of the diastolic depolarization in sinoatrial tissue and Purkinje fibers. Alinidine shows antiischemic and antiarrhythmic effects[1][2].
Product Specifications
CAS Number
33178-86-8
Product Name Alternative
St-567
UNSPSC
12352005
Hazard Statement
H301-H315-H319-H335
Target
Potassium Channel
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/alinidine.html
Smiles
ClC1=CC=CC(Cl)=C1N(CC=C)C2=NCCN2
Molecular Formula
C12H13Cl2N3
Molecular Weight
270.16
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
References & Citations
[1]Snyders DJ, et al. Alinidine modifies the pacemaker current in sheep Purkinje fibers. Pflugers Arch. 1987;410 (1-2) :83-91.|[2]J L Challinor-Rogers, et al. Antiischemic and antiarrhythmic activities of some novel alinidine analogs in the rat heart. J Cardiovasc Pharmacol. 1997 Apr;29 (4) :499-507.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Phase 3
Available Sizes
Frequently Asked Questions
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