5-Hydroxy-2'-deoxyuridine
5-Hydroxy-2'-deoxyuridine (5-OHdU) is a major stable oxidation product of 2'-Deoxycytidine. 5-Hydroxy-2'-deoxyuridine can be incorporated into DNA in vitro by DNA polymerase[1].
Product Specifications
CAS Number
[5168-36-5]
Product Name Alternative
5-OHdU
UNSPSC
12352005
Hazard Statement
H315, H319, H320
Target
Endogenous Metabolite
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/5-hydroxy-2-deoxyuridine.html
Purity
99.77
Solubility
DMSO : 33.33 mg/mL (ultrasonic) |H2O : 10 mg/mL (ultrasonic)
Smiles
O[C@H]1C[C@H](N2C(NC(C(O)=C2)=O)=O)O[C@@H]1CO
Molecular Formula
C9H12N2O6
Molecular Weight
244.20
Precautions
H315, H319, H320
References & Citations
[1]Purmal AA, et al. Major oxidative products of cytosine, 5-hydroxycytosine and 5-hydroxyuracil, exhibit sequence context-dependent mispairing in vitro. Nucleic Acids Res. 1994 Jan 11;22 (1) :72-8.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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