LasR-IN-5
LasR-IN-5 (compound 3C) is a LasR antagonist with an IC50 of 1.37 μM, demonstrating a 77% inhibition of biofilm formation in Pseudomonas aeruginosa. LasR-IN-5 also exhibits quorum sensing (QS) inhibition activity and has potential applications in Pseudomonas aeruginosa infection research[1].
Product Specifications
UNSPSC
12352005
Target
Antibiotic; Bacterial
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/lasr-in-5.html
Smiles
CN(CC1)CCN1C(C=C2)=CC=C2/C=C(C#N)/C3=NC4=CC=CC=C4S3
Molecular Formula
C21H20N4S
Molecular Weight
360.48
References & Citations
[1]Mohammed EZ, et al. Design, synthesis, and molecular dynamic simulations of some novel benzo[d]thiazoles with anti-virulence activity against Pseudomonas aeruginosa. Eur J Med Chem. 2024 Sep 14;279:116880.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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