FR 64822

FR 64822 is a dopamine D2 receptor agonist that can induce antinociceptive activity in rats and mice by indirectly stimulating dopamine D2 receptors. FR 64822 can promote penile erection in juvenile rats and improve amnesia in rats induced by scopolamine during passive avoidance tasks[1].

Product Specifications

CAS Number

[102671-35-2]

UNSPSC

12352005

Target

Dopamine Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein; Neuronal Signaling

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/fr-64822.html

Smiles

O=C(NN1CC=CCC1)NC2=CC=NC=C2

Molecular Formula

C11H14N4O

Molecular Weight

218.26

References & Citations

[1]Ohkubo Y, et al. Involvement of dopamine in the mechanism of action of FR64822, a novel non-opioid antinociceptive compound. Eur J Pharmacol. 1991 Nov 5;204 (2) :121-5. |[2]Maeda N, et al. A screening concept based on a hypothesis led to the development of a putative cognitive enhancer that stimulates penile erection. Jpn J Pharmacol. 1994 Mar;64 (3) :147-53.