Human CA8 Protein

<strong>Human CA8 Protein</strong>_x000D_ <strong>Catalog number:</strong> B2011668_x000D_ <strong>Lot number:</strong> Batch Dependent_x000D_ <strong>Expiration Date:</strong> Batch dependent_x000D_ <strong>Amount:</strong> 100 µg_x000D_ <strong>Molecular Weight or Concentration:</strong> 1 mg/mL_x000D_ <strong>Supplied as:</strong> Solution_x000D_ <strong>Applications:</strong> molecular tool for various biochemical applications_x000D_ <strong>Storage:</strong> -20 °C_x000D_ <strong>Keywords:</strong> CA8, CARP protein, CA-8, Carbonic anhydrase-related protein protein, CAMRQ3 protein, CA-VIII protein, CA 8, CA 8 protein, CA-8 protein, CALS protein_x000D_ <strong>Grade:</strong> Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity &gt;18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ <strong>References:</strong>_x000D_ 1: Chi TH, Hsieh BY, Liang PS, Han TH, Hsieh M. Expression and Functional Study of Single Mutations of Carbonic Anhydrase 8 in Neuronal Cells Cell Mol Neurobiol. 2021 Aug;41(6):1355-1371._x000D_ 2: Wang TK, Cheng CK, Chi TH, Ma YS, Wu SB, Wei YH, Hsieh M. Effects of carbonic anhydrase-related protein VIII on human cells harbouring an A8344G mitochondrial DNA mutation Biochem J. 2014 Apr 1;459(1):149-60._x000D_ 3: Hsieh M, Hsieh BY, Ma CY, Li YT, Liu CS, Lo CM. Protective roles of carbonic anhydrase 8 in Machado-Joseph Disease J Neurosci Res. 2019 Oct;97(10):1278-1297._x000D_ 4: Fu ES, Erasso DM, Zhuang GZ, Upadhyay U, Ozdemir M, Wiltshire T, Sarantopoulos KD, Smith SB, Maixner W, Martin ER, Levitt RC. Impact of human CA8 on thermal antinociception in relation to morphine equivalence in mice Neuroreport. 2017 Dec 13;28(18):1215-1220._x000D_ 5: Wang TK, Lin YM, Lo CM, Tang CH, Teng CL, Chao WT, Wu MH, Liu CS, Hsieh M. Oncogenic roles of carbonic anhydrase 8 in human osteosarcoma cells Tumour Biol. 2016 Jun;37(6):7989-8005._x000D_ 6: Huang MS, Wang TK, Liu YW, Li YT, Chi TH, Chou CW, Hsieh M. Roles of carbonic anhydrase 8 in neuronal cells and zebrafish Biochim Biophys Acta. 2014 Sep;1840(9):2829-42._x000D_ 7: Ma HL, Yu SJ, Chen J, Ding XF, Chen G, Liang Y, Pan JL. CA8 promotes RCC proliferation and migration though its expression level is lower in tumor compared to adjacent normal tissue Biomed Pharmacother. 2020 Jan;121:109578._x000D_ 8: Upadhyay U, Zhuang GZ, Diatchenko L, Parisien M, Kang Y, Sarantopoulos KD, Martin ER, Smith SB, Maixner W, Levitt RC. Reversion mutation of cDNA CA8-204 minigene construct produces a truncated functional peptide that regulates calcium release in vitro and produces profound analgesia in vivo Mamm Genome. 2020 Dec;31(9-12):287-294._x000D_ 9: Upadhyay U, Zhuang GZ, Diatchenko L, Parisien M, Kang Y, Sarantopoulos KD, Martin ER, Smith SB, Maixner W, Levitt RC. Profound analgesia is associated with a truncated peptide resulting from tissue specific alternative splicing of DRG CA8-204 regulated by an exon-level cis-eQTL PLoS Genet. 2019 Jun 14;15(6):e1008226._x000D_ <a href="https://pubmed.ncbi.nlm.nih.gov/29407793">10: Lo CM, Ma YS, Wei YH, Hsieh BYT, Hsieh M. Promoter analysis and transcriptional regulation of human carbonic anhydrase VIII gene in a MERRF disease cell model Arch Biochem Biophys. 2018 Mar 1;641:50-61. </a>_x000D_ _x000D_ <strong>Products Related to Human CA8 Protein can be found at</strong> <a href="https://moleculardepot.com/product-category/Proteins/"> Proteins</a>