Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

Withanolide A

Withanolide A is an orally active extract from the Indian herb Ashwagandha. Withanolide A can induce apoptosis. Withanolide A has anti-inflammatory and antitumor activity. Withanolide A can be used in the study of neurodegenerative diseases[1][2][3][4].

Product Specifications

CAS Number

32911-62-9

UNSPSC

12352005

Target

Apoptosis; Notch

Type

Natural Products

Related Pathways

Apoptosis; Neuronal Signaling; Stem Cell/Wnt

Applications

Neuroscience-Neuromodulation

Field of Research

Cancer; Inflammation/Immunology; Neurological Disease

Assay Protocol

https://www.medchemexpress.com/withanolide-a.html

Purity

99.98

Solubility

DMSO : 10 mg/mL (ultrasonic)

Smiles

O=C1O[C@@]([H])([C@@](C)([C@H]2CC[C@]3([C@@]4([C@H]5[C@@H]([C@@](O)(CC=CC6=O)[C@]6([C@]4(CC[C@@]32C)[H])C)O5)[H])[H])O)CC(C)=C1C

Molecular Formula

C28H38O6

Molecular Weight

470.60

References & Citations

[1]Kuboyama T, et al. Neuritic regeneration and synaptic reconstruction induced by withanolide A. Br J Pharmacol. 2005 Apr;144 (7) :961-71..|[2]Zhang X, et al. Inhibition of cell growth and induction of apoptosis in ovarian carcinoma cell lines CaOV3 and SKOV3 by natural withanolide Withaferin A. Gynecol Oncol. 2012 Mar;124 (3) :606-12.|[3]Pathak P, et al. Standardized root extract of Withania somnifera and Withanolide A exert moderate vasorelaxant effect in the rat aortic rings by enhancing nitric oxide generation. J Ethnopharmacol. 2021 Oct 5;278:114296.|[4]Baitharu I, et al. Withanolide A prevents neurodegeneration by modulating hippocampal glutathione biosynthesis during hypoxia. PLoS One. 2014 Oct 13;9 (10) :e105311.

Shipping Conditions

Blue Ice

Storage Conditions

-20°C (Powder, protect from light)

Scientific Category

Natural Products

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

More Discoveries

Explore Other Products

Browse additional items from our catalog

Recombinant Human B4GAT1/B3GNT1 Protein (His Tag)
PKSH032105-01 10 µg

Recombinant Human B4GAT1/B3GNT1 Protein (His Tag)

Sign In for Pricing
View Details
Recombinant Human B4GAT1/B3GNT1 Protein (His Tag)
PKSH032105-02 50 µg

Recombinant Human B4GAT1/B3GNT1 Protein (His Tag)

Sign In for Pricing
View Details
Etheno-2’-deoxy-Beta-D-adenosine 5’-Monophosphate Sodium Salt
TRC-E890388-5MG 5 mg

Etheno-2’-deoxy-Beta-D-adenosine 5’-Monophosphate Sodium Salt

Sign In for Pricing
View Details
Phospho-eIF4EBP1 (T70) Recombinant Rabbit monoclonal Antibody
HA751360 100 µL

Phospho-eIF4EBP1 (T70) Recombinant Rabbit monoclonal Antibody

Sign In for Pricing
View Details
JAK2 Human Gene Knockout Kit (CRISPR)
KN220503 1 Kit

JAK2 Human Gene Knockout Kit (CRISPR)

Sign In for Pricing
View Details
H2BC18 (NM_001024599) Human Over-expression Lysate
LY422516 100 µg

H2BC18 (NM_001024599) Human Over-expression Lysate

Sign In for Pricing
View Details