BRD4 degrader-4
BRD4 degrader-4 (Compound 1-f) is a BRD4 degrader. BRD4 degrader-4 can be used for the research of cancer and other bromodomain related diseases[1].
Product Specifications
CAS Number
[2851986-83-7]
UNSPSC
12352005
Hazard Statement
H302-H315-H319
Target
Epigenetic Reader Domain
Type
Reference compound
Related Pathways
Epigenetics
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/protac-brd4-degrader-25.html
Solubility
10 mM in DMSO
Smiles
CC1=C(C)SC2=C1C(C3=CC=C(C4=CC(NC(C5=C6N(C=CC=N6)N=C5)=O)=C(C=C4)F)C=C3)=N[C@@H](CC(N(C)C)=O)C7=NN=C(C)N27
Molecular Formula
C34H30FN9O2S
Molecular Weight
647.72
Precautions
P264-P270-P280-P302+P352-P305+P351+P338-P330-P362+P364-P501
References & Citations
[1]Bailey S, et al. Preparation of aminobiarylthienotriazolodiazepinylacetamide derivatives for use as BRD4 modulators. WO2022221786A2. 2022-10-20.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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