SIM1 rabbit pAb
SIM1 and SIM2 genes are Drosophila single-minded (sim) gene homologs. SIM1 transcript was detected only in fetal kidney out of various adult and fetal tissues tested. Since the sim gene plays an important role in Drosophila development and has peak levels of expression during the period of neurogenesis, it was proposed that the human SIM gene is a candidate for involvement in certain dysmorphic features (particularly the facial and skull characteristics), abnormalities of brain development, and/or mental retardation of Down syndrome. [provided by RefSeq, Jul 2008],
Product Specifications
Background
Synonyms
Single-minded homolog 1 (Class E basic helix-loop-helix protein 14) (bHLHe14)
Gene ID
6492
UniProt
P81133
Cellular Locus
Nucleus.
Host
Rabbit
Species Reactivity
Human,Mouse
Reactivity
Human; Mouse
Immunogen
Synthesized peptide derived from human SIM1 AA range: 545-595
Clonality
Polyclonal
Isotype
IgG
Source
Rabbit
Applications
WB
Validated Applications
WB
Stability
-20°C/1 year
Concentration
1 mg/mL
Dilution
WB 1:500-2000
Molecular Weight
85kD
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.
Product Datasheet
https://www.elkbiotech.com/upload/file/Antibodies/pAb/ES13102-1.pdf
Observed Molecular Weight
85 kD
Subcellular Location
Nucleus .
Other Product Names
Single-minded homolog 1 (Class E basic helix-loop-helix protein 14) (bHLHe14)
Gene ID (Human)
6492
SwissProt (Human)
P81133
Available Sizes
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