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(R) -BRD3731

(R) -BRD3731 is a GSK3 inhibitor extracted from patent US20160375006A1, compound example 273, has IC50s of 1.05 and 6.7 μM for GSK3β and GSK3α, respectively[1].

Product Specifications

CAS Number

2056262-08-7

UNSPSC

12352005

Target

GSK-3

Type

Reference compound

Related Pathways

PI3K/Akt/mTOR; Stem Cell/Wnt

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/brd3731.html

Purity

98.22

Solubility

DMSO : 200 mg/mL (ultrasonic)

Smiles

O=C1C2=C(N=C3C([C@@]2(C)C4=CC=CC=C4)=C(CC(C)(C)C)NN3)CC(C)(C)C1

Molecular Formula

C24H31N3O

Molecular Weight

377.52

References & Citations

[1]Scolnick E, et, al. Uses of paralog-selective inhibitors of gsk3 kinases. US20160375006A1.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

GSK-3α; GSK-3β

Available Sizes

Frequently Asked Questions

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