(R) -BRD3731
(R) -BRD3731 is a GSK3 inhibitor extracted from patent US20160375006A1, compound example 273, has IC50s of 1.05 and 6.7 μM for GSK3β and GSK3α, respectively[1].
Product Specifications
CAS Number
2056262-08-7
UNSPSC
12352005
Target
GSK-3
Type
Reference compound
Related Pathways
PI3K/Akt/mTOR; Stem Cell/Wnt
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/brd3731.html
Purity
98.22
Solubility
DMSO : 200 mg/mL (ultrasonic)
Smiles
O=C1C2=C(N=C3C([C@@]2(C)C4=CC=CC=C4)=C(CC(C)(C)C)NN3)CC(C)(C)C1
Molecular Formula
C24H31N3O
Molecular Weight
377.52
References & Citations
[1]Scolnick E, et, al. Uses of paralog-selective inhibitors of gsk3 kinases. US20160375006A1.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
GSK-3α; GSK-3β
Available Sizes
Frequently Asked Questions
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