Stafia-1-dipivaloyloxymethyl ester
Stafia-1-dipivaloyloxymethyl ester (compound 27, 0-200 μM) decreases pSTAT5a expression significantly, and has no obvious inhibition on pSTAT5b[1].
Product Specifications
CAS Number
[2582755-72-2]
UNSPSC
12352005
Target
STAT
Type
Reference compound
Related Pathways
JAK/STAT Signaling; Stem Cell/Wnt
Applications
COVID-19-immunoregulation
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/stafia-1-dipivaloyloxymethyl-ester.html
Purity
95.38
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C(C(C)(C)C)OCOP(OCOC(C(C)(C)C)=O)(C(C1=CC(C2=CC(OC)=C(OC)C(OC)=C2)=CC(C3=CC(OC)=C(C(OC)=C3)OC)=C1)F)=O
Molecular Formula
C37H48FO13P
Molecular Weight
750.74
References & Citations
[1]Kalaiselvi Natarajan, et al. Stafia-1: A STAT5a-Selective Inhibitor Developed via Docking-Based Screening of in Silico O-Phosphorylated Fragments. Chemistry. 2020 Jan 2;26 (1) :148-154.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
STAT5
Available Sizes
Curated Selection
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