Benzamidine (hydrochloride hydrate)
Product Specifications
UNSPSC Description
Benzamidine (Benzenecarboximidamide) hydrochloride hydrate is a reversible competitive trypsin-like serine proteases inhibitor with Kis of 20, 21, 97, 110, 320 and 750 μM against Tryptase, Trypsin, uPA, Factor Xa, Thrombin and tPA, respectively[1][2].
Target Antigen
Ser/Thr Protease
Type
Biochemical Assay Reagents
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/benzamidine-hydrochloride-hydrate.html
Purity
99.96
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
N=C(C1=CC=CC=C1)N.[H]Cl.[H]O[H].[x]
References & Citations
[1]Katz BA, et al. Structural basis for selectivity of a small molecule, S1-binding, submicromolar inhibitor of urokinase-type plasminogen activator. Chem Biol. 2000 Apr;7(4):299-312.|[2]J A Cairns, et al. Mast cell tryptase stimulates the synthesis of type I collagen in human lung fibroblasts. J Clin Invest. 1997 Mar 15;99(6):1313-21.
Shipping Conditions
Room Temperature
Storage Conditions
Store at room temperature 3 years
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-W087937/Benzamidine-hydrochloride-hydrate-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-W087937/Benzamidine-hydrochloride-hydrate-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
206752-36-5
Available Sizes
Curated Selection
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