Santalol

Santalol is a mixture of α and β-isomer santalol. α-Santalol is found in sandalwood oil. α-Santalol is a promising anti-cancer agent against cancers such as oral, breast, prostate and skin cancer. Santalol has sedative activity [1][2][3].

Product Specifications

CAS Number

[11031-45-1]

UNSPSC

12352211

Hazard Statement

H315, H319, H335

Target

Apoptosis

Type

Natural Products

Related Pathways

Apoptosis

Applications

Cancer-programmed cell death

Field of Research

Cancer; Neurological Disease

Assay Protocol

https://www.medchemexpress.com/santalol.html

Purity

74.30

Solubility

DMSO : 50 mg/mL (ultrasonic)

Smiles

C=C1[C@@H]2C[C@H]([C@]1(C)CC/C=C(C)\CO)CC2.C[C@@]3(C4([C@H]5CC3CC45)C)CC/C=C(CO)/C.[mixtureofaandb-isomer]

Molecular Formula

C15H24O

Molecular Weight

220.36

Precautions

H315, H319, H335

References & Citations

[1]Bommareddy A, et al. Medicinal properties of alpha-santalol, a naturally occurring constituent of sandalwood oil: review.Nat Prod Res. 2019 Feb;33 (4) :527-543.|[2]Bommareddy A, et al. Akt/survivin pathway inhibition enhances the apoptotic cell death-induced by alpha-santalol in human prostate cancer cells. Fitoterapia. 2020 Jun;143:104552. |[3]Okugawa H, et al. Effect of α-santalol and β-santalol from sandalwood on the central nervous system in mice. Phytomedicine. 1995 Oct;2 (2) :119-26.